Ontology highlight
ABSTRACT:
SUBMITTER: Sakashita A
PROVIDER: S-EPMC4689518 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Sakashita Akihiko A Kawabata Yukiko Y Jincho Yuko Y Tajima Shiun S Kumamoto Soichiro S Kobayashi Hisato H Matsui Yasuhisa Y Kono Tomohiro T
PloS one 20151223 12
In mice, primordial germ cells migrate into the genital ridges by embryonic day 13.5 (E13.5), where they are then subjected to a sex-specific fate with female and male primordial germ cells undergoing mitotic arrest and meiosis, respectively. However, the sex-specific basis of primordial germ cell differentiation is poorly understood. The aim of this study was to investigate the sex-specific features of mouse primordial germ cells. We performed RNA-sequencing (seq) of E13.5 female and male mouse ...[more]