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Cancer and the gut microbiota: an unexpected link.


ABSTRACT: Changes in the interactions among the gut microbiota, intestinal epithelium, and host immune system are associated with many diseases, including cancer. We discuss how environmental factors infuence this cross-talk during oncogenesis and tumor progression and how manipulations of the gut microbiota might improve the clinical activity of anticancer agents.

SUBMITTER: Zitvogel L 

PROVIDER: S-EPMC4690201 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature

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Cancer and the gut microbiota: an unexpected link.

Zitvogel Laurence L   Galluzzi Lorenzo L   Viaud Sophie S   Vétizou Marie M   Daillère Romain R   Merad Miriam M   Kroemer Guido G  

Science translational medicine 20150101 271


Changes in the interactions among the gut microbiota, intestinal epithelium, and host immune system are associated with many diseases, including cancer. We discuss how environmental factors infuence this cross-talk during oncogenesis and tumor progression and how manipulations of the gut microbiota might improve the clinical activity of anticancer agents. ...[more]

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