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LymPHOS 2.0: an update of a phosphosite database of primary human T cells.

ABSTRACT: LymPHOS is a web-oriented database containing peptide and protein sequences and spectrometric information on the phosphoproteome of primary human T-Lymphocytes. Current release 2.0 contains 15 566 phosphorylation sites from 8273 unique phosphopeptides and 4937 proteins, which correspond to a 45-fold increase over the original database description. It now includes quantitative data on phosphorylation changes after time-dependent treatment with activators of the TCR-mediated signal transduction pathway. Sequence data quality has also been improved with the use of multiple search engines for database searching. LymPHOS can be publicly accessed at http://www.lymphos.org. Database URL: http://www.lymphos.org.

SUBMITTER: Nguyen TD

PROVIDER: S-EPMC4691341 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature

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LymPHOS 2.0: an update of a phosphosite database of primary human T cells.

Nguyen Tien Dung TD Vidal-Cortes Oriol O Gallardo Oscar O Abian Joaquin J Carrascal Montserrat M

Database : the journal of biological databases and curation 20151226

LymPHOS is a web-oriented database containing peptide and protein sequences and spectrometric information on the phosphoproteome of primary human T-Lymphocytes. Current release 2.0 contains 15 566 phosphorylation sites from 8273 unique phosphopeptides and 4937 proteins, which correspond to a 45-fold increase over the original database description. It now includes quantitative data on phosphorylation changes after time-dependent treatment with activators of the TCR-mediated signal transduction pa ...[more]

PMID: 26708986

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