A revised model for estimating g-ratio from MRI.
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ABSTRACT:
SUBMITTER: West KL
PROVIDER: S-EPMC4691384 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Publications
A revised model for estimating g-ratio from MRI.
West Kathryn L KL Kelm Nathaniel D ND Carson Robert P RP Does Mark D MD
NeuroImage 20150820
A key measure of white matter health is the g-ratio, which is defined as the ratio between the inner axon radius and the outer, myelinated, axon radius. Recent methods have been proposed to measure the g-ratio non-invasively using the relationship between two magnetic resonance imaging (MRI) measures. While this relationship is intuitive, it predicates on the simplifying assumption that g-ratio is constant across axons. Here, we extend the model to account for a distribution of g-ratio values wi ...[more]
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