Ontology highlight
ABSTRACT:
SUBMITTER: Salminen LE
PROVIDER: S-EPMC4692153 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Salminen Lauren E LE Schofield Peter R PR Pierce Kerrie D KD Zhao Yi Y Luo Xi X Wang Youdan Y Laidlaw David H DH Cabeen Ryan P RP Conturo Thomas E TE Tate David F DF Akbudak Erbil E Lane Elizabeth M EM Heaps Jodi M JM Bolzenius Jacob D JD Baker Laurie M LM Cagle Lee M LM Paul Robert H RH
Behavioural brain research 20150828
The common angiotensinogen (AGT) M268T polymorphism (rs699; historically referred to as M235T) has been identified as a significant risk factor for cerebrovascular pathologies, yet it is unclear if healthy older adults carrying the threonine amino acid variant have a greater risk for white matter damage in specific fiber tracts. Further, the impact of the threonine variant on cognitive function remains unknown. The present study utilized multiple indices of diffusion tensor imaging (DTI) and neu ...[more]