Ontology highlight
ABSTRACT:
SUBMITTER: Mathy N
PROVIDER: S-EPMC4693643 | biostudies-literature | 2004 May
REPOSITORIES: biostudies-literature
Mathy Nathalie N Pellegrini Olivier O Serganov Alexander A Patel Dinshaw J DJ Ehresmann Chantal C Portier Claude C
Molecular microbiology 20040501 3
The ribosomal protein S15 binds to 16S rRNA, during ribosome assembly, and to its own mRNA (rpsO mRNA), affecting autocontrol of its expression. In both cases, the RNA binding site is bipartite with a common subsite consisting of a G*U/G-C motif. The second subsite is located in a three-way junction in 16S rRNA and in the distal part of a stem forming a pseudoknot in Escherichia coli rpsO mRNA. To determine the extent of mimicry between these two RNA targets, we determined which amino acids inte ...[more]