Ontology highlight
ABSTRACT:
SUBMITTER: Burnetti AJ
PROVIDER: S-EPMC4694762 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Burnetti Anthony J AJ Aydin Mert M Buchler Nicolas E NE
Molecular biology of the cell 20151104 1
Cells have evolved oscillators with different frequencies to coordinate periodic processes. Here we studied the interaction of two oscillators, the cell division cycle (CDC) and the yeast metabolic cycle (YMC), in budding yeast. Previous work suggested that the CDC and YMC interact to separate high oxygen consumption (HOC) from DNA replication to prevent genetic damage. To test this hypothesis, we grew diverse strains in chemostat and measured DNA replication and oxygen consumption with high tem ...[more]