Ontology highlight
ABSTRACT:
SUBMITTER: Lin HP
PROVIDER: S-EPMC4694976 | biostudies-literature | 2015 Sep
REPOSITORIES: biostudies-literature
Lin Hui-Ping HP Lin Ching-Yu CY Huo Chieh C Jan Yee-Jee YJ Tseng Jen-Chih JC Jiang Shih Sheng SS Kuo Ying-Yu YY Chen Shyh-Chang SC Wang Chih-Ting CT Chan Tzu-Min TM Liou Jun-Yang JY Wang John J Chang Wun-Shaing Wayne WS Chang Chung-Ho CH Kung Hsing-Jien HJ Chuu Chih-Pin CP
Oncotarget 20150901 29
The qRT-PCR analysis of 139 clinical samples and analysis of 150 on-line database clinical samples indicated that AKT3 mRNA expression level was elevated in primary prostate tumors. Immunohistochemical staining of 65 clinical samples revealed that AKT3 protein expression was higher in prostate tumors of stage I, II, III as compared to nearby normal tissues. Plasmid overexpression of AKT3 promoted cell proliferation of LNCaP, PC-3, DU-145, and CA-HPV-10 human prostate cancer (PCa) cells, while kn ...[more]