Ontology highlight
ABSTRACT:
SUBMITTER: Leonard J
PROVIDER: S-EPMC4695335 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Cell reports 20151210 11
Condensin is a conserved chromosomal complex necessary to promote mitotic chromosome condensation and sister chromatid resolution during anaphase. Here, we report that yeast condensin binds to replicated centromere regions. We show that centromeric condensin relocalizes to chromosome arms as cells undergo anaphase segregation. We find that condensin relocalization is initiated immediately after the bipolar attachment of sister kinetochores to spindles and requires Polo kinase activity. Moreover, ...[more]