Is targeted therapy feasible in acute myelogenous leukemia?
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ABSTRACT:
SUBMITTER: Konig H
PROVIDER: S-EPMC4696009 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
Publications
Is targeted therapy feasible in acute myelogenous leukemia?
Current hematologic malignancy reports 20140601 2
The prognosis for patients with acute myeloid leukemia (AML) is determined to a large degree by the biology of the leukemic cell. In recent years, the identification and characterization of genetic aberrations has vastly improved our understanding of the pathogenesis of AML. In contrast, however, there has been a lack of clinically meaningful therapeutic advances. The same chemotherapeutic strategies have been applied to AML for several decades now, and while these regimens are effective in indu ...[more]
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