Clinical utility of gene-expression profiling in women with early breast cancer: an overview of systematic reviews.
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ABSTRACT:
SUBMITTER: Marrone M
PROVIDER: S-EPMC4698966 | biostudies-literature | 2015 Jul
REPOSITORIES: biostudies-literature
Publications
Clinical utility of gene-expression profiling in women with early breast cancer: an overview of systematic reviews.
Marrone Michael M Stewart Alison A Dotson W David WD
Genetics in medicine : official journal of the American College of Medical Genetics 20141204 7
<h4>Purpose</h4>This overview systematically evaluates the clinical utility of using Oncotype DX and MammaPrint gene-expression profiling tests to direct treatment decisions in women with breast cancer. The findings are intended to inform an updated recommendation from the Evaluation of Genomic Applications in Practice and Prevention Working Group.<h4>Methods</h4>Evidence reported in systematic reviews evaluating the clinical utility of Oncotype DX and MammaPrint, as well as the ability to predi ...[more]
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