Ontology highlight
ABSTRACT:
SUBMITTER: Kishan AU
PROVIDER: S-EPMC4699266 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Kishan Amar U AU McCloskey Susan A SA
Therapeutic advances in medical oncology 20160101 1
Postmastectomy radiotherapy (PMRT) has been shown to decrease locoregional recurrence and improve overall survival in patients with tumors greater than 5 cm or positive nodes. Because neoadjuvant chemotherapy (NAC) can cause significant downstaging, the indications for PMRT in the setting of NAC remain controversial and thus careful consideration of clinical stage at presentation, pathologic response to NAC, and other clinical characteristics, such as grade and biomarker status is required. The ...[more]