Ontology highlight
ABSTRACT:
SUBMITTER: Hunt M
PROVIDER: S-EPMC4699355 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Genome biology 20151229
The assembly of DNA sequence data is undergoing a renaissance thanks to emerging technologies capable of producing reads tens of kilobases long. Assembling complete bacterial and small eukaryotic genomes is now possible, but the final step of circularizing sequences remains unsolved. Here we present Circlator, the first tool to automate assembly circularization and produce accurate linear representations of circular sequences. Using Pacific Biosciences and Oxford Nanopore data, Circlator correct ...[more]