Ontology highlight
ABSTRACT:
SUBMITTER: Shi YZ
PROVIDER: S-EPMC4701004 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Shi Ya-Zhou YZ Jin Lei L Wang Feng-Hua FH Zhu Xiao-Long XL Tan Zhi-Jie ZJ
Biophysical journal 20151201 12
A full understanding of RNA-mediated biology would require the knowledge of three-dimensional (3D) structures, structural flexibility, and stability of RNAs. To predict RNA 3D structures and stability, we have previously proposed a three-bead coarse-grained predictive model with implicit salt/solvent potentials. In this study, we further develop the model by improving the implicit-salt electrostatic potential and including a sequence-dependent coaxial stacking potential to enable the model to si ...[more]