Ontology highlight
ABSTRACT:
SUBMITTER: Bernstein DI
PROVIDER: S-EPMC4701617 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Bernstein David I DI Munoz Flor M FM Callahan S Todd ST Rupp Richard R Wootton Susan H SH Edwards Kathryn M KM Turley Christine B CB Stanberry Lawrence R LR Patel Shital M SM Mcneal Monica M MM Pichon Sylvie S Amegashie Cyrille C Bellamy Abbie R AR
Vaccine 20151202 3
<h4>Background</h4>Cytomegalovirus (CMV) is a leading cause of congenital infection and an important target for vaccine development.<h4>Methods</h4>CMV seronegative girls between 12 and 17 years of age received CMV glycoprotein B (gB) vaccine with MF59 or saline placebo at 0, 1 and 6 months. Blood and urine were collected throughout the study for evidence of CMV infection based on PCR and/or seroconversion to non-vaccine CMV antigens.<h4>Results</h4>402 CMV seronegative subjects were vaccinated ...[more]