Dataset Information
Computational identification of putative miRNAs and their target genes in pathogenic amoeba Naegleria fowleri.
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ABSTRACT:
SUBMITTER: Padmashree D
PROVIDER: S-EPMC4702033 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Publications
Computational identification of putative miRNAs and their target genes in pathogenic amoeba Naegleria fowleri.
Bioinformation 20151231 12
Naegleria fowleri is a parasitic unicellular free living eukaryotic amoeba. The parasite spreads through contaminated water and causes primary amoebic meningoencephalitis (PAM). Therefore, it is of interest to understand its molecular pathogenesis. Hence, we analyzed the parasite genome for miRNAs (microRNAs) that are non-coding, single stranded RNA molecules. We identified 245 miRNAs using computational methods in N. fowleri, of which five miRNAs are conserved. The predicted miRNA targets were ...[more]
