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Biocuration of functional annotation at the European nucleotide archive.

ABSTRACT: The European Nucleotide Archive (ENA; http://www.ebi.ac.uk/ena) is a repository for the submission, maintenance and presentation of nucleotide sequence data and related sample and experimental information. In this article we report on ENA in 2015 regarding general activity, notable published data sets and major achievements. This is followed by a focus on sustainable biocuration of functional annotation, an area which has particularly felt the pressure of sequencing growth. The importance of functional annotation, how it can be submitted and the shifting role of the biocurator in the context of increasing volumes of data are all discussed.

SUBMITTER: Gibson R

PROVIDER: S-EPMC4702917 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature

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Biocuration of functional annotation at the European nucleotide archive.

Gibson Richard R Alako Blaise B Amid Clara C Cerdeño-Tárraga Ana A Cleland Iain I Goodgame Neil N Ten Hoopen Petra P Jayathilaka Suran S Kay Simon S Leinonen Rasko R Liu Xin X Pallreddy Swapna S Pakseresht Nima N Rajan Jeena J Rosselló Marc M Silvester Nicole N Smirnov Dmitriy D Toribio Ana Luisa AL Vaughan Daniel D Zalunin Vadim V Cochrane Guy G

Nucleic acids research 20151128 D1

The European Nucleotide Archive (ENA; http://www.ebi.ac.uk/ena) is a repository for the submission, maintenance and presentation of nucleotide sequence data and related sample and experimental information. In this article we report on ENA in 2015 regarding general activity, notable published data sets and major achievements. This is followed by a focus on sustainable biocuration of functional annotation, an area which has particularly felt the pressure of sequencing growth. The importance of fun ...[more]

PMID: 26615190

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