Subjective responses to alcohol consumption as endophenotypes: advancing behavioral genetics in etiological and treatment models of alcoholism.
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ABSTRACT:
SUBMITTER: Ray LA
PROVIDER: S-EPMC4703313 | biostudies-literature | 2010 Sep
REPOSITORIES: biostudies-literature
Publications
Subjective responses to alcohol consumption as endophenotypes: advancing behavioral genetics in etiological and treatment models of alcoholism.
Ray Lara A LA Mackillop James J Monti Peter M PM
Substance use & misuse 20100901 11
Individual differences in subjective responses to alcohol consumption represent genetically mediated biobehavioral mechanisms of alcoholism risk (i.e., endophenotype). The objective of this review is three-fold: (1) to provide a critical review the literature on subjective response to alcohol and to discuss the rationale for its conceptualization as an endophenotype for alcoholism; (2) to examine the literature on the neurobiological substrates and associated genetic factors subserving individua ...[more]
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