Ontology highlight
ABSTRACT:
SUBMITTER: Pineda LC
PROVIDER: S-EPMC4703883 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
Pineda Leslie C LC Watt Kevin M KM
Clinics in perinatology 20141127 1
To prevent the devastating consequences of infection, most infants admitted to the neonatal intensive care unit are exposed to antibiotics. However, dosing regimens are often extrapolated from data in adults and older children, increasing the risk for drug toxicity and lack of clinical efficacy because they fail to account for developmental changes in infant physiology. However, newer technologies are emerging with minimal-risk study designs, including ultra-low-volume assays, pharmacokinetic mo ...[more]