Ontology highlight
ABSTRACT:
SUBMITTER: Ray S
PROVIDER: S-EPMC4704721 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
G3 (Bethesda, Md.) 20151123 1
The developmental transition to motherhood requires gene expression changes that alter the brain to drive the female to perform maternal behaviors. We broadly examined the global transcriptional response in the mouse maternal brain, by examining four brain regions: hypothalamus, hippocampus, neocortex, and cerebellum, in virgin females, two pregnancy time points, and three postpartum time points. We find that overall there are hundreds of differentially expressed genes, but each brain region and ...[more]