Ontology highlight
ABSTRACT:
SUBMITTER: Nersisyan L
PROVIDER: S-EPMC4706054 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
F1000Research 20150805
Cell signaling pathways are sequences of biochemical reactions that propagate an input signal, such as a hormone binding to a cell-surface receptor, into the cell to trigger a reactive process. Assessment of pathway activities is crucial for determining which pathways play roles in disease versus normal conditions. To date various pathway flow/perturbation assessment tools are available, however they are constrained to specific algorithms and specific data types. There are no accepted standards ...[more]