Ontology highlight
ABSTRACT:
SUBMITTER: Ruark E
PROVIDER: S-EPMC4706061 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Ruark Elise E Münz Márton M Renwick Anthony A Clarke Matthew M Ramsay Emma E Hanks Sandra S Mahamdallie Shazia S Elliott Anna A Seal Sheila S Strydom Ann A Gerton Lunter L Rahman Nazneen N
F1000Research 20150922
To enhance knowledge of gene variation in outbred populations, and to provide a dataset with utility in research and clinical genomics, we performed exome sequencing of 1,000 UK individuals from the general population and applied a high-quality analysis pipeline that includes high sensitivity and specificity for indel detection. Each UK individual has, on average, 21,978 gene variants including 160 rare (0.1%) variants not present in any other individual in the series. These data provide a basel ...[more]