Vinculin expression in MC3T3-E1 cells in response to mechanical stimulus.
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ABSTRACT:
SUBMITTER: Cora-Cruz JJ
PROVIDER: S-EPMC4706558 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
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Vinculin expression in MC3T3-E1 cells in response to mechanical stimulus.
Cora-Cruz J J JJ Diffoot-Carlo N N Sundaram P A PA
Data in brief 20151205
Loading frequency is known to influence the expression of the focal adhesions of the adherent cells. A small cyclical tensile force was transmitted to mouse pre-osteoblast MC3T3-E1 cells through PDMS substrates of varying stiffness. Changes in cell behavior with respect to proliferation and characteristics of focal adhesions were quantified through immunofluorescence labeling of vinculin. Amount of inactive vinculin was higher on substrates subjected to cyclic stimulation when compared with the ...[more]
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