Data in support of alpha1beta1 and integrin-linked kinase interact and modulate angiotensin II effects in vascular smooth muscle cells.
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ABSTRACT:
SUBMITTER: Moraes JA
PROVIDER: S-EPMC4706604 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
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Data in support of alpha1beta1 and integrin-linked kinase interact and modulate angiotensin II effects in vascular smooth muscle cells.
Moraes João Alfredo JA Frony Ana Clara AC Dias Aline Maria AM Renovato-Martins Mariana M Rodrigues Genilson G Marcinkiewicz Cezary C Assreuy Jamil J Barja-Fidalgo Christina C
Data in brief 20151217
The data provides information in support of the research article Moraes et al., Atherosclerosis 243(2) (2015) 477-485 [1]. Here we provide data behind the mechanisms involved in Angiotensin II (Ang II) effects on vascular smooth muscle cells (VSMC). Ang II-induced VSMC ROS production is modulated by alpha1beta1 integrin. Ang II also stimulates ROS production in VSMC via p47 (phox) , a NOX2 subunit. Furthermore, Ang II effect on VSMC migration was also inhibited by NOX2 inhibitor. We showed that ...[more]
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