Ontology highlight
ABSTRACT:
SUBMITTER: Greenwood TA
PROVIDER: S-EPMC4707095 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Greenwood Tiffany A TA Lazzeroni Laura C LC Calkins Monica E ME Freedman Robert R Green Michael F MF Gur Raquel E RE Gur Ruben C RC Light Gregory A GA Nuechterlein Keith H KH Olincy Ann A Radant Allen D AD Seidman Larry J LJ Siever Larry J LJ Silverman Jeremy M JM Stone William S WS Sugar Catherine A CA Swerdlow Neal R NR Tsuang Debby W DW Tsuang Ming T MT Turetsky Bruce I BI Braff David L DL
Schizophrenia research 20151118 1
The Consortium on the Genetics of Schizophrenia Family Study (COGS-1) has previously reported our efforts to characterize the genetic architecture of 12 primary endophenotypes for schizophrenia. We now report the characterization of 13 additional measures derived from the same endophenotype test paradigms in the COGS-1 families. Nine of the measures were found to discriminate between schizophrenia patients and controls, were significantly heritable (31 to 62%), and were sufficiently independent ...[more]