Ontology highlight
ABSTRACT:
SUBMITTER: Fujiwara R
PROVIDER: S-EPMC4708261 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Fujiwara Ryoichi R Maruo Yoshihiro Y Chen Shujuan S Tukey Robert H RH
Toxicology and applied pharmacology 20150902 1
Newborns commonly develop physiological hyperbilirubinemia (also known as jaundice). With increased bilirubin levels being observed in breast-fed infants, breast-feeding has been recognized as a contributing factor for the development of neonatal hyperbilirubinemia. Bilirubin undergoes selective metabolism by UDP-glucuronosyltransferase (UGT) 1A1 and becomes a water soluble glucuronide. Although several factors such as gestational age, dehydration and weight loss, and increased enterohepatic cir ...[more]