Genome-Wide Analysis Reveals Novel Regulators of Growth in Drosophila melanogaster.
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ABSTRACT:
SUBMITTER: Vonesch SC
PROVIDER: S-EPMC4709145 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Publications
Genome-Wide Analysis Reveals Novel Regulators of Growth in Drosophila melanogaster.
Vonesch Sibylle Chantal SC Lamparter David D Mackay Trudy F C TF Bergmann Sven S Hafen Ernst E
PLoS genetics 20160111 1
Organismal size depends on the interplay between genetic and environmental factors. Genome-wide association (GWA) analyses in humans have implied many genes in the control of height but suffer from the inability to control the environment. Genetic analyses in Drosophila have identified conserved signaling pathways controlling size; however, how these pathways control phenotypic diversity is unclear. We performed GWA of size traits using the Drosophila Genetic Reference Panel of inbred, sequenced ...[more]
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