Ontology highlight
ABSTRACT:
SUBMITTER: Gruene TM
PROVIDER: S-EPMC4709260 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Gruene Tina M TM Flick Katelyn K Stefano Alexis A Shea Stephen D SD Shansky Rebecca M RM
eLife 20151114
Traditional rodent models of Pavlovian fear conditioning assess the strength of learning by quantifying freezing responses. However, sole reliance on this measure includes the de facto assumption that any locomotor activity reflects an absence of fear. Consequently, alternative expressions of associative learning are rarely considered. Here we identify a novel, active fear response ('darting') that occurs primarily in female rats. In females, darting exhibits the characteristics of a learned fea ...[more]