Ontology highlight
ABSTRACT:
SUBMITTER: Davis KA
PROVIDER: S-EPMC4710355 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Davis Kathryn Adamiak KA Nanga Ravi Prakash Reddy RP Das Sandhitsu S Chen Stephanie H SH Hadar Peter N PN Pollard John R JR Lucas Timothy H TH Shinohara Russell T RT Litt Brian B Hariharan Hari H Elliott Mark A MA Detre John A JA Reddy Ravinder R
Science translational medicine 20151001 309
When neuroimaging reveals a brain lesion, drug-resistant epilepsy patients show better outcomes after resective surgery than do the one-third of drug-resistant epilepsy patients who have normal brain magnetic resonance imaging (MRI). We applied a glutamate imaging method, GluCEST (glutamate chemical exchange saturation transfer), to patients with nonlesional temporal lobe epilepsy based on conventional MRI. GluCEST correctly lateralized the temporal lobe seizure focus on visual and quantitative ...[more]