Ontology highlight
ABSTRACT:
SUBMITTER: Randlett O
PROVIDER: S-EPMC4710481 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Nature methods 20151101 11
In order to localize the neural circuits involved in generating behaviors, it is necessary to assign activity onto anatomical maps of the nervous system. Using brain registration across hundreds of larval zebrafish, we have built an expandable open-source atlas containing molecular labels and definitions of anatomical regions, the Z-Brain. Using this platform and immunohistochemical detection of phosphorylated extracellular signal–regulated kinase (ERK) as a readout of neural activity, we have d ...[more]