Ontology highlight
ABSTRACT:
SUBMITTER: Schlesiger MI
PROVIDER: S-EPMC4711275 | biostudies-literature | 2015 Aug
REPOSITORIES: biostudies-literature
Schlesiger Magdalene I MI Cannova Christopher C CC Boublil Brittney L BL Hales Jena B JB Mankin Emily A EA Brandon Mark P MP Leutgeb Jill K JK Leibold Christian C Leutgeb Stefan S
Nature neuroscience 20150629 8
The superficial layers of the medial entorhinal cortex (MEC) are a major input to the hippocampus. The high proportion of spatially modulated cells, including grid cells and border cells, in these layers suggests that MEC inputs are critical for the representation of space in the hippocampus. However, selective manipulations of the MEC do not completely abolish hippocampal spatial firing. To determine whether other hippocampal firing characteristics depend more critically on MEC inputs, we recor ...[more]