Ontology highlight
ABSTRACT:
SUBMITTER: Buckley CE
PROVIDER: S-EPMC4712025 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Buckley Clare E CE Moore Rachel E RE Reade Anna A Goldberg Anna R AR Weiner Orion D OD Clarke Jonathan D W JDW
Developmental cell 20160101 1
We demonstrate the utility of the phytochrome system to rapidly and reversibly recruit proteins to specific subcellular regions within specific cells in a living vertebrate embryo. Light-induced heterodimerization using the phytochrome system has previously been used as a powerful tool to dissect signaling pathways for single cells in culture but has not previously been used to reversibly manipulate the precise subcellular location of proteins in multicellular organisms. Here we report the exper ...[more]