Ontology highlight
ABSTRACT:
SUBMITTER: van Ast VA
PROVIDER: S-EPMC4712793 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
van Ast V A VA Spicer J J Smith E E EE Schmer-Galunder S S Liberzon I I Abelson J L JL Wager T D TD
Cerebral cortex (New York, N.Y. : 1991) 20140923 2
Social threat can have adverse effects on cognitive performance, but the brain mechanisms underlying its effects are poorly understood. We investigated the effects of social evaluative threat on working memory (WM), a core component of many important cognitive capabilities. Social threat impaired WM performance during an N-back task and produced widespread reductions in activation in lateral prefrontal cortex and intraparietal sulcus (IPS), among other regions. In addition, activity in frontal a ...[more]