Dataset Information

The lifetime economic burden of keratoconus: a decision analysis using a markov model.

ABSTRACT:

Purpose

To estimate the expected incremental lifetime cost of treatment of keratoconus compared to the expected cost of the treatment of myopia.

Design

Cost estimate from the patient's perspective using a Markov decision model.

Methods

We modeled a hypothetical cohort of people with clinically significant incident keratoconus as defined by the Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study. We included costs of clinic visits, fitting fees, contact lenses, surgical procedures, and complications. Survival curves of corneal transplants and associated complications were modeled using data from the 2007 Australian Graft Registry. Medical treatment regimens after surgery were defined by expert opinion.