Underweight as a risk factor for respiratory death in the Whitehall cohort study: exploring reverse causality using a 45-year follow-up.
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ABSTRACT:
SUBMITTER: Kivimaki M
PROVIDER: S-EPMC4717419 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Publications
Underweight as a risk factor for respiratory death in the Whitehall cohort study: exploring reverse causality using a 45-year follow-up.
Kivimäki Mika M Shipley Martin J MJ Bell Joshua A JA Brunner Eric J EJ Batty G David GD Singh-Manoux Archana A
Thorax 20150807 1
Underweight adults have higher rates of respiratory death than the normal weight but it is unclear whether this association is causal or reflects illness-induced weight loss (reverse causality). Evidence from a 45-year follow-up of underweight participants for respiratory mortality in the Whitehall study (N=18 823; 2139 respiratory deaths) suggests that excess risk among the underweight is attributable to reverse causality. The age-adjusted and smoking-adjusted risk was 1.55-fold (95% CI 1.32 to ...[more]
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