MicroRNAs Expressed during Viral Infection: Biomarker Potential and Therapeutic Considerations.
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ABSTRACT:
SUBMITTER: Louten J
PROVIDER: S-EPMC4718089 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Publications
MicroRNAs Expressed during Viral Infection: Biomarker Potential and Therapeutic Considerations.
Louten Jennifer J Beach Michael M Palermino Kristina K Weeks Maria M Holenstein Gabrielle G
Biomarker insights 20150101 Suppl 4
MicroRNAs (miRNAs) are short sequences of noncoding single-stranded RNAs that exhibit inhibitory effects on complementary target mRNAs. Recently, it has been discovered that certain viruses express their own miRNAs, while other viruses activate the transcription of cellular miRNAs for their own benefit. This review summarizes the viral and/or cellular miRNAs that are transcribed during infection, with a focus on the biomarker and therapeutic potential of miRNAs (or their antagomirs). Several hum ...[more]
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