Introducing MINA--The Molecularly Imprinted Nanoparticle Assay.
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ABSTRACT:
SUBMITTER: Shutov RV
PROVIDER: S-EPMC4719181 | biostudies-literature | 2014 Mar
REPOSITORIES: biostudies-literature
Publications
Introducing MINA--The Molecularly Imprinted Nanoparticle Assay.
Shutov Roman V RV Guerreiro Antonio A Moczko Ewa E de Vargas-Sansalvador Isabel Perez IP Chianella Iva I Whitcombe Michael J MJ Piletsky Sergey A SA
Small (Weinheim an der Bergstrasse, Germany) 20140206 6
A new ELISA- (enzyme-linked immunosorbent assay)-like assay is demonstrated in which no elements of biological origin are used for molecular recognition or signaling. Composite imprinted nanoparticles that contain a catalytic core and which are synthesized by using a solid-phase approach can simultaneously act as recognition/signaling elements, and be used with minimal modifications to standard assay protocols. This assay provides a new route towards replacement of unstable biomolecules in immun ...[more]
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