Dataset Information

Inflow-vascular space occupancy (iVASO) reproducibility in the hippocampus and cortex at different blood water nulling times.

ABSTRACT: Inflow-vascular space occupancy (iVASO) measures arterial cerebral blood volume (aCBV) using accurate blood water nulling (inversion time [TI]) when arterial blood reaches the capillary, i.e., at the arterial arrival time. This work assessed the reproducibility of iVASO measurements in the hippocampus and cortex at multiple TIs.The iVASO approach was implemented at multiple TIs in 10 healthy volunteers at 3 Tesla. aCBV values were measured at each TI in the left and right hippocampus, and the cortex. Reproducibility of aCBV measurements within scans (same day) and across sessions (different days) was assessed using the intraclass correlation coefficient (ICC).Overall hippocampal aCBV was significantly higher than cortical aCBV, likely due to higher gray matter volume. Hippocampal ICC values were high at short TIs (?914 ms; intrascan values?=?0.80-0.96, interscan values?=?0.61-0.91). Cortically, high ICC values were observed at intermediate TIs of 914 (intra: 0.93, inter: 0.87) and 1034 ms (intra: 0.96, inter: 0.86). The ICC values were comparable to established contrast-based CBV measures.iVASO measurements are reproducible within and across sessions. TIs for iVASO measurements should be chosen carefully, taking into account heterogeneous arterial arrival times in different brain regions. Magn Reson Med 75:2379-2387, 2016. © 2015 Wiley Periodicals, Inc.

SUBMITTER: Rane S

PROVIDER: S-EPMC4720590 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature

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Inflow-vascular space occupancy (iVASO) reproducibility in the hippocampus and cortex at different blood water nulling times.

Rane Swati S Talati Pratik P Donahue Manus J MJ Heckers Stephan S

Magnetic resonance in medicine 20150720 6

<h4>Purpose</h4>Inflow-vascular space occupancy (iVASO) measures arterial cerebral blood volume (aCBV) using accurate blood water nulling (inversion time [TI]) when arterial blood reaches the capillary, i.e., at the arterial arrival time. This work assessed the reproducibility of iVASO measurements in the hippocampus and cortex at multiple TIs.<h4>Methods</h4>The iVASO approach was implemented at multiple TIs in 10 healthy volunteers at 3 Tesla. aCBV values were measured at each TI in the left a ...[more]

PMID: 26192478

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Project description:Delimiting the habitat characteristics describing the environmental conditions required by a species has become a critical tool for predicting organismal responses to environmental change. Grinnell emphasized the effects of environmental factors on the ability of a population to maintain a positive growth rate, yet few studies have included demographic or reproductive data in analyses of the Grinnellian niche. Identifying differences in habitat exploitation patterns in response to structural variation in the environment presents an incomplete description of the ability of species to adapt to changing habitats if demographic traits are not included. We estimated the vegetation characteristics used by individuals within a population of hooded warblers (Setophaga citrina) across a spatial transect that includes three structurally different forest habitats. We predicted individuals should select similar structural characteristics within each habitat and have similar reproductive success across sample sites. In the two years post burn, adults were present but no young fledged indicating the habitat requirements necessary for reproduction were absent in this habitat. We found significant differences in habitat space occupied by individuals in unaltered and harvested habitats. Nesting habitats used by female warblers differed from available habitat. Fledging success was lower in the harvested habitat 10 to 12 years post-harvest. In the harvested habitat, fledging success was greater on mesic slopes but decreased along a habitat gradient to xeric ridgetops, suggesting compensation in habitat use does not ameliorate fitness costs. In contrast, there was no difference in the number of fledged young along this gradient in the unaltered habitat. Based solely on occupancy data, traditional ecological niche models would incorrectly conclude the environmental characteristics found across the three forested habitats are included in the Grinnellian niche of the hooded warbler. However, examination of demographic and environmental data simultaneously allows differentiation between occupied habitat space and niche space.

Dataset Information

Inflow-vascular space occupancy (iVASO) reproducibility in the hippocampus and cortex at different blood water nulling times.

Publications

Inflow-vascular space occupancy (iVASO) reproducibility in the hippocampus and cortex at different blood water nulling times.

Similar Datasets

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