Ontology highlight
ABSTRACT:
SUBMITTER: Riddler SA
PROVIDER: S-EPMC4721905 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Riddler Sharon A SA Aga Evgenia E Bosch Ronald J RJ Bastow Barbara B Bedison Margaret M Vagratian David D Vaida Florin F Eron Joseph J JJ Gandhi Rajesh T RT Mellors John W JW
The Journal of infectious diseases 20150902 4
<h4>Unlabelled</h4>We measured plasma human immunodeficiency virus type 1 (HIV-1) RNA levels by means of single-copy assay in 334 participants receiving virologically suppressive antiretroviral therapy (ART). A residual viremia load of ≥1 copy/mL after 4 years of ART was predicted by a higher pre-ART HIV-1 RNA level, higher CD8(+) T-cell count during treatment, and a lower ratio of CD4+ T cells to CD8+ T cells during treatment but not by initial ART regimen. In a longitudinal subset of 64 indivi ...[more]