Ontology highlight
ABSTRACT:
SUBMITTER: Hecht ES
PROVIDER: S-EPMC4722804 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Hecht Elizabeth S ES Scholl Elizabeth H EH Walker S Hunter SH Taylor Amber D AD Cliby William A WA Motsinger-Reif Alison A AA Muddiman David C DC
Journal of proteome research 20150914 10
An early-stage, population-wide biomarker for ovarian cancer (OVC) is essential to reverse its high mortality rate. Aberrant glycosylation by OVC has been reported, but studies have yet to identify an N-glycan with sufficiently high specificity. We curated a human biorepository of 82 case-control plasma samples, with 27%, 12%, 46%, and 15% falling across stages I-IV, respectively. For relative quantitation, glycans were analyzed by the individuality normalization when labeling with glycan hydraz ...[more]