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A case of kidney transplantation using donation after circulatory death with renal calculi.


ABSTRACT: Donation after circulatory death (DCD) supplies a big percentage of the organ source pool. Compared to living-related donations, donor kidneys from DCD are commonly with lower quality since they inevitably suffer from hypoxia, hypotension, and inadequate organ perfusion during the progression to circulatory arrest. The current case presents a 44-year-old male donor with wide range subarachnoid hemorrhage and multiple skull fracture from a car accident. Multiple stones were detected in his right kidney. We performed a modified ex vivo pyelolithotomy and ureteroscopy on the bench to render a stone-free allograft. We also improved the donor kidney with hypothermic/perfusion preservation machine before renal transplantation. The recipient showed no complications during the first two-month post-operational follow-up. Such a donor kidney with stones may probably be discarded by conventional perspective. Yet, the combination of the ex vivo bench-surgery technique and hypothermic oxygenation/perfusion makes it a qualified donor kidney. Thus we have demonstrated a promising way of saving borderline qualified DCD donor kidneys.

SUBMITTER: Gao B 

PROVIDER: S-EPMC4724018 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature

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A case of kidney transplantation using donation after circulatory death with renal calculi.

Gao Baoshan B   Zhang Kun K   Guo Chunjie C   Wang Weigang W   Wang Gang G   Wang Yuantao Y   Yao Liyu L   Fu Yaowen Y   Zhou Honglan H  

International journal of clinical and experimental medicine 20151115 11


Donation after circulatory death (DCD) supplies a big percentage of the organ source pool. Compared to living-related donations, donor kidneys from DCD are commonly with lower quality since they inevitably suffer from hypoxia, hypotension, and inadequate organ perfusion during the progression to circulatory arrest. The current case presents a 44-year-old male donor with wide range subarachnoid hemorrhage and multiple skull fracture from a car accident. Multiple stones were detected in his right  ...[more]

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