Ontology highlight
ABSTRACT:
SUBMITTER: Suh H
PROVIDER: S-EPMC4724063 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Molecular cell 20160101 2
Dynamic interactions between RNA polymerase II and various mRNA-processing and chromatin-modifying enzymes are mediated by the changing phosphorylation pattern on the C-terminal domain (CTD) of polymerase subunit Rpb1 during different stages of transcription. Phosphorylations within the repetitive heptamer sequence (YSPTSPS) of CTD have primarily been defined using antibodies, but these do not distinguish different repeats or allow comparative quantitation. Using a CTD modified for mass spectrom ...[more]