Ontology highlight
ABSTRACT:
SUBMITTER: Li C
PROVIDER: S-EPMC4724690 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Li Chao C Song Xiaowei X Song Junke J Pang Xiaocong X Wang Zhe Z Zhao Ying Y Lian Wenwen W Liu Ailin A Du Guanhua G
Acta pharmaceutica Sinica. B 20151129 1
The pharmacokinetic profile of gallocatechin-7-gallate (J10688) was studied in rats after intravenous administration. Male and female Sprague-Dawley (SD) rats received 1, 3, and 10 mg/kg (i.v.) of J10688 and plasma drug concentrations were determined by a high performance liquid chromatography-mass spectrometry (LC-MS) method. The pharmacokinetic software Data Analysis System (Version 3.0) was used to calculate the pharmacokinetic parameters. For different i.v. doses of J10688, the mean peak pla ...[more]