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Acupuncture for neurogenesis in experimental ischemic stroke: a systematic review and meta-analysis.


ABSTRACT: Acupuncture has been used for patients with stroke and post-stroke rehabilitation for thousands of years. Previous studies reported that acupuncture enhanced stroke recovery through neurogenesis. Hence, we conducted a systematic review and meta-analysis for preclinical studies to assess the current evidence for acupuncture effect on neurogenesis in treating ischaemic stroke. Studies were obtained from six databases, including PubMed, EMBASE, Cochrane Library, Chinese National Knowledge Infrastructure, VIP information database, and Chinese Biomedical Literature Database, Ultimately, 34 studies containing 1617 animals were identified. Neurogenesis markers of Brdu, Nestin, PSA-NCAM, NeuN and GFAP were selected as major outcomes. The pooled results of 15 studies marked with Brdu showed significant effects of acupuncture for improving proliferation when compared with control groups (P?

SUBMITTER: Lu L 

PROVIDER: S-EPMC4726177 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature

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Acupuncture for neurogenesis in experimental ischemic stroke: a systematic review and meta-analysis.

Lu Lin L   Zhang Xiao-guang XG   Zhong Linda L D LL   Chen Zi-xian ZX   Li Yan Y   Zheng Guo-qing GQ   Bian Zhao-xiang ZX  

Scientific reports 20160120


Acupuncture has been used for patients with stroke and post-stroke rehabilitation for thousands of years. Previous studies reported that acupuncture enhanced stroke recovery through neurogenesis. Hence, we conducted a systematic review and meta-analysis for preclinical studies to assess the current evidence for acupuncture effect on neurogenesis in treating ischaemic stroke. Studies were obtained from six databases, including PubMed, EMBASE, Cochrane Library, Chinese National Knowledge Infrastru  ...[more]

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