Ontology highlight
ABSTRACT:
SUBMITTER: Fan J
PROVIDER: S-EPMC4726187 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Fan Jiangli J Han Zhichao Z Kang Yao Y Peng Xiaojun X
Scientific reports 20160122
Lysosome-specific fluorescent probes are exclusive to elucidate the functions of lysosomal thiols. Moreover, two-photon microscopy offers advantages of less phototoxicity, better three dimensional spatial localization, deeper penetration depth and lower self-absorption. However, such fluorescent probes for thiols are still rare. In this work, an efficient two-photon fluorophore 1,8-naphthalimide-based probe conjugating a 2,4-dinitrobenzenesulfonyl chloride and morpholine was designed and synthes ...[more]