Exploration of nucleosome positioning patterns in transcription factor function.
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ABSTRACT:
SUBMITTER: Maehara K
PROVIDER: S-EPMC4726364 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Publications
Exploration of nucleosome positioning patterns in transcription factor function.
Maehara Kazumitsu K Ohkawa Yasuyuki Y
Scientific reports 20160121
The binding of transcription factors (TFs) triggers activation of specific chromatin regions through the recruitment and activation of RNA polymerase. Unique nucleosome positioning (NP) occurs during gene expression and has been suggested to be involved in various other chromatin functions. However, the diversity of NP that can occur for each function has not been clarified. Here we used MNase-Seq data to evaluate NP around 258 cis-regulatory elements in the mouse genome. Principal component ana ...[more]
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