Comprehensive analyses of how tubule occlusion and advanced glycation end-products diminish strength of aged dentin.

ABSTRACT: In clinical dentistry, since fracture is a major cause of tooth loss, better understanding of mechanical properties of teeth structures is important. Dentin, the major hard tissue of teeth, has similar composition to bone. In this study, we investigated the mechanical properties of human dentin not only in terms of mineral density but also using structural and quality parameters as recently accepted in evaluating bone strength. Aged crown and root dentin (age ≥ 40) exhibited significantly lower flexural strength and toughness than young dentin (age < 40). Aged dentin, in which the dentinal tubules were occluded with calcified material, recorded the highest mineral density; but showed significantly lower flexural strength than young dentin. Dentin with strong alignment of the c-axis in hydr

SUBMITTER: Shinno Y 

PROVIDER: S-EPMC4726429 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature