Lung Infection by Human Bocavirus Induces the Release of Profibrotic Mediator Cytokines In Vivo and In Vitro.
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ABSTRACT:
SUBMITTER: Khalfaoui S
PROVIDER: S-EPMC4726461 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Publications
Lung Infection by Human Bocavirus Induces the Release of Profibrotic Mediator Cytokines In Vivo and In Vitro.
Khalfaoui Soumaya S Eichhorn Vivien V Karagiannidis Christian C Bayh Inga I Brockmann Michael M Pieper Monika M Windisch Wolfram W Schildgen Oliver O Schildgen Verena V
PloS one 20160125 1
Human Bocavirus subtype 1 (HBoV1) is associated with respiratory diseases and may contribute to chronic lung diseases by persisting in the infected host. Here the question was addressed if HBoV infections could contribute to fibrogenesis processes as suggested by previously published clinical observations. Cytokine profiles induced by HBoV infection in CuFi-8 air-liquid interphase cell cultures and in bronchoalveolar lavage fluid (BALF) of 20 HBoV-positive and 12 HBoV-negative patients were anal ...[more]
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