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A Useful Modification of the Evans Magnesium Halide-Catalyzed anti-Aldol Reaction: Application to Enolizable Aldehydes.

ABSTRACT: A practical protocol for use of the magnesium halide-catalyzed anti-aldol reaction of an Evans N-acyloxazolidinone with enolizable aldehydes is reported. The yields of anti-aldol adducts for saturated or unsaturated and branched or unbranched aliphatic aldehydes are preparatively useful.

SUBMITTER: May AE

PROVIDER: S-EPMC4727177 | biostudies-literature | 2010

REPOSITORIES: biostudies-literature

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A Useful Modification of the Evans Magnesium Halide-Catalyzed anti-Aldol Reaction: Application to Enolizable Aldehydes.

May Aaron E AE Connell Nathan T NT Dahlmann Heidi A HA Hoye Thomas R TR

Synlett : accounts and rapid communications in synthetic organic chemistry 20100101

A practical protocol for use of the magnesium halide-catalyzed anti-aldol reaction of an Evans N-acyloxazolidinone with enolizable aldehydes is reported. The yields of anti-aldol adducts for saturated or unsaturated and branched or unbranched aliphatic aldehydes are preparatively useful. ...[more]

PMID: 26823643

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