Ontology highlight
ABSTRACT:
SUBMITTER: de Jong OG
PROVIDER: S-EPMC4727569 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
de Jong Olivier G OG van Balkom Bas W M BW Gremmels Hendrik H Verhaar Marianne C MC
Journal of cellular and molecular medicine 20151127 2
Exosomes are important mediators of intercellular communication. Additionally, they contain a variety of components capable of interacting with the extracellular matrix (ECM), including integrins, matrix metalloproteinases and members of the immunoglobin superfamily. Despite these observations, research on exosome-ECM interactions is limited. Here, we investigate whether the exosome-associated lysyl oxidase family member lysyl oxidase-like 2 (LOXL2) is involved in ECM remodelling. We found that ...[more]